Recent research articles

Arsenic Contamination of Groundwater in South and East Asian Countries
Volume I: Policy Report Full Report (1,038kb pdf)
Volume II: Technical Report Full Report  (2,879kb pdf)
Paper 1: Arsenic Occurence in Groundwater in South and East Asia -- Scale, Causes, and Mititgation (715kb)
Paper 2: An Overview of Current Operational Responses to the Arsenic Issue in South and East Asia  (413kb)
Paper 3: Arsenic Mitigation Technologies in South and East Asia (345kb)
Paper 4: The Economics of Arsenic Mitigation (335kb)

Ahmad, B Goldar, and S Misra.Value of arsenic-free drinking water to rural households in Bangladesh .  J Environ Manage, January 1, 2005; 74(2): 173-85.


Ineffectiveness and Poor Reliability of Arsenic Removal Plants in West Bengal, India
Envirn. Sci. & Technolo. xxx, xxx  (June 2005)

In Bundschuh, J., Bhattacharya, P. & Chandrashekharam, D. (Eds.) Natural Arsenic in Groundwater, Occurrence, Remediation and Management. A.A. Balkema Publishers, Taylor and Francis Group, London, pp. 319-330 (2005)

BT Beaulieu and KS Savage,  
Arsenate adsorption structures on aluminum oxide and phyllosilicate mineral surfaces in smelter-impacted soils.

Environ Sci Technol, 2005; 39(10): 3571-9.

DK Das, TK Garai, S Sarkar, and Pur.
Interaction of arsenic with zinc and organics in a rice (Oryza sativa L.)--cultivated field in India. 
Scientific World Journal, 2005; 5: 646-51.

S von Ehrenstein, D N Guha Mazumder, Yan Yuan, Sambit Samanta, John Balmes, Arabinda Sil, Nilima Ghosh, Meera Hira-Smith, Reina Haque, Radhika Purushothamam, Sarbari Lahiri, Subhankar Das, and Allan H Smith.
Decrements in lung function related to arsenic in drinking water in West Bengal, India.
Am. J. Epidemiol., August 10, 2005.

A Van Geen, Z Cheng, AA Seddique, MA Hoque, A Gelman, JH Graziano, H Ahsan, F Parvez, and KM Ahmed.

Reliability of a commercial kit to test groundwater for arsenic in Bangladesh.  Environ Sci Technol, January 1, 2005; 39(1): 299-303.
Comment by Mukherjee et al. andresponse

Graziano, J.H, and A. Van Geen  (2005)
Reducing Arsenic Exposure from Drinking Water:  Different Settings call for Different Approaches 
Environmental Health  Perspectives 113(6), A360-A361 (editorial)
DM Hafeman, H Ahsan, ED Louis, AB Siddique, V Slavkovich, Z Cheng, A van Geen, and JH Graziano
Association between arsenic exposure and a measure of subclinical sensory neuropathy in Bangladesh.
J Occup Environ Med,2005; 47(8): 778-84.

A. Howe, LH Fung, G Lalor, R Rattray  and M Vutchkov.  2005.Elemental composition of Jamaican foods

1: A survey of five food crop categories.
Environ. Geochem. Hlth. 27:19-30.

Jakariya M, Rahman M, Chowdhury AMR, Rahman M, Yunus M, Bhuiya A, Wahed MA, Bhattachariya P, Jack G, Vahter M, Persson LA.

Sustainable safe water option  in Bangladesh. Experiences in Bangladesh
M Jang, JS Hwang, SI Choi, and JK Park. Remediation of arsenic-contaminated soils and washing effluents. Chemosphere, July 1, 2005;60(3): 344-54.

EM Kenyon, LM Del Razo and MF Hughes. 2005.
Tissue distribution and urinary excretion of inorganic arsenic and its methylated metabolites in mice following acute oral administration of arwsenate.
Toxicol Sci 85:468-475.

MW Lai, EW Boyer, ME Kleinman, NM Rodig, and MB Ewald. 
Acute arsenic poisoning in two siblings.
PEDIATRICS, 2005, 116, 249-257

Tamar Lasky, Wenyu Sun, Abdel Kadry, and Michael K. Hoffman  
Mean Total Arsenic Concentrations in Chicken 1989-2000 and Estimated Exposures for Consumers of Chicken  
Environmental Health Perspectives Volume 112, Number 1 January 2005

 Lee, L and Bebb, G. 2005. 
A case of Bowens Disease and small-cell carcinoma: Long-term consequences ,of chronic arsenic exposure in Chinese traditional medicine.

Environ Hlth Perspect 113: 2-7-210 .

PC Lee, I-C Ho and T-C Lee. 2005.  Oxidative stress mediates sodium arsenite-induced expression of heme oxygenase-1, monocyte chemoattractant protein-1, and interleukin-6 in vascular smooth muscle. Toxicol Sci 85:541-550.

 L Lien and RT Wilkin.High-level arsenite removal from groundwater by zero-valent iron .

Lowney, YW, MV Ruby, RC Wester, RA Schoof, SE Holm, XY Hui, S Barbadillo, and HI Maibach. 
Percutaneous absorption of arsenic from environmental media.
Toxicol Ind Health,2005; 21: 1-14.

M Lu, H Wang, XF Li, X Lu, WR Cullen, LL Arnold, SM Cohen, and XC Le,Evidence of hemoglobin binding to arsenic as a basis for the accumulation of arsenic in rat blood.   Chem Res Toxicol, December 1, 2004; 17(12): 1733-42.

Mead, M.N., (2005)
Arsenic: in Search for an antidote to a global poison
Environmental Health  Perspectives 113(6), A379-A386

Maria Mercedes Meza et al.,
Arsenic Metabolism: Association between Urinary Methylated Arsenic andCYT19 Polymorphisms in Children.

Environmental Health Perspectives, Vol. 113, No. 6, June 2005.

Abul Hasnat Milton, Wayne Smith,  Bayzidur Rahman,  Ziaul Hasan,  Umme Kulsum, Keith Dear, M. Rakibuddin, and Azahar Ali.Chronic Arsenic Exposure and Adverse Pregnancy Outcomes in Bangladesh.

JC Ng, JP Wang, B Zheng, C Zhai, R Maddalena, F Liu, and MR Moore.
Urinary porphyrins as biomarkers for arsenic exposure among susceptible populations in Guizhou province, China.
Toxicology and Applied Pharmacology, 2005, 206(2), 176-184.

RS Oremland, TR Kulp, JS Blum, SE Hoeft, S Baesman, LG Miller, and JF Stolz.  Science. A Microbial Arsenic Cycle in a Salt-Saturated, Extreme Environment,308, 2005: 1305-1308.

 R. Sharma and S. Pervez. 2005.Toxic metals in human blood and breast milk samples in an integrated steel plant environment in Central India.
Environ. Geochem. Hlth. 27:39-45.

Tamar L. , Wenyu Sun, Abdel Kadry, and Michael K. Hoffman  
Mean Total Arsenic Concentrations in Chicken 1989-2000 and Estimated Exposures for Consumers of Chicken 
Environmental Health Perspectives Volume 112, Number 1 January 2004

AH Milton, W Smith, B Rahman, Z Hasan, U Kulsum, K Dear, M Rakibuddin, and A Ali

Chronic arsenic exposure and adverse pregnancy outcomes in Bangladesh
Epidemiology, January 1, 2005; 16(1): 82-6.


T Nakajima, YH Xu, Y Mori, M Kishita, H Takanashi, S Maeda, and A Ohk
Combined use of photocatalyst and adsorbent for the removal of inorganic arsenic(III) and organoarsenic compounds from aqueous media. 
J Hazard Mater, April 11, 2005; 120(1-3): 75-80.

JC Ng, JP Wang, B Zheng, C Zhai, R Maddalena, F Liu, and MR Moore.

Urinary porphyrins as biomarkers for arsenic exposure among susceptible populations in Guizhou province, China.
Toxicology and Applied Pharmacology, 2005, 206(2), 176-184.

Ronald S. Oremlanda,  and John F. Stolzb.
Arsenic, microbes and contaminated aquifers.
Trends in Microbiology, 13(2), pp 45-49 ,February 2005,.

KS Patel, K Shrivas, R Brandt, N Jakubowski, W Corns, and P Hoffmann

Arsenic contamination in water, soil, sediment and rice of central India;16003581

Environ Geochem Health, April 1, 2005; 27(2): 131-45.

KB Payne and TM Abdel-Fattah.
Adsorption of arsenate and arsenite by iron-treated activated carbon and zeolites: effects of pH, temperature, and ionic strength.
 J Environ Sci Health A Tox Hazard Subst. Environ. Eng, 2005; 40(4): 723-49.

T Phenrat, TF Marhaba, and M Rachakornkij.
A SEM and X-ray study for investigation of solidified/stabilized arsenic-iron hydroxide sludge.   
J Hazard Mater, 2005; 118(1-3): 185-95

M. Quaghebeur, A. Rate, Z. Rengel, and C. Hinz.
Desorption Kinetics of Arsenate from Kaolinite as Influenced by pH,
2005. J. Environ. Qual. 34:479-486.

 MM Rahman, MK Sengupta, S Ahamed, UK Chowdhury, D Lodh, A Hossain, B Das, N Roy, KC Saha, SK Palit, and DChakraborti.  
Arsenic contamination of groundwater and its health impact on residents in a village in West Bengal, India.  
Bull World Health Organ, January 1, 2005; 83(1): 49-57


Sudipta Sarkar, Anirban Gupta, Ranjan K. Biswas, Arun K. Deb, John E.Greenleaf and Arup K. SenGupta. 

Well-head arsenic removal units in remote villages of Indian subcontinent: Field results and performance evaluation. 
Water Research, 2005, 39, 2196-2206  pdf file

A. Sen Gupta

Well-head arsenic removal units in remote villages in Indian subcontinent: Field results and performance evaluation.

Water Research. 39, 2196-2206. (2005)

contact Dr. Anirban Gupta (e-mail guptaanirban @

S. Shivaji, K. Suresh, Preeti Chaturvedi, Smita Dube and S. Sengupta. Int J Syst Evol Microbiol 55 (2005), 1123-1127Singh, T.S. and Pant, K.KBacillus arsenicus sp. nov., an arsenic-resistant bacterium isolated from a siderite concretion in West Bengal, India.A comparative study for the removal of As(III) and As(V) by activated alumina
In Bundschuh, J., Bhattacharya, P. & Chandrashekharam, D. (Eds.) Natural Arsenic in GroundwaterOccurrence, Remediation and Management. A.A. Balkema Publishers, Taylor and Francis Group, London, pp. 211-222 (2005)


PG Smith, I Koch, RA Gordon, DF Mandoli, BD Chapman, and KJ Reimer.
X-ray absorption near-edge structure analysis of arsenic species forapplication to biological environmental samples.  
Environ Sci Technol, January 1, 2005;39(1): 248-54.


Sinha D, Roy M, Siddiqi M, Bhattacharya.Arsenic-induced micronuclei formation in Mammalian cells and its counteraction by tea.  
 J Environ Pathol Toxicol Oncol. 2005;24(1):45-56.

Gordon Stanger, To Van Truong, K S Le Thi My Ngoc, T V Luyen, and Tuyen Tran.  Thanh,
Arsenic in groundwaters of the Lower Mekong
Environ Geochem Health, 2005; 27(4): 341-357.

Soile Tapio. Combined effects of gamma radiation and arsenite on the proteome of human TK6 lymphoblastoid cell (Mutat Res. 2005 Mar 7;581(1-2):141-52 )
Tollestrup, K, FJ Frost, M Cristiaani, GP McMillan, RL Calderon and RS Padilla. 
Arsenic-induced skin conditions identified in southwest dermatology  practices: An epidemiological tool.

Environ Geochem Hlth 2005.27:47-53 

Ahmed N. Uddin , Fredric J. Burns , and Toby G. Rossman
Vitamin E and organoselenium prevent the cocarcinogenic activity of arsenite with solar UV in mouse skin
Carcinogenesis Advance Access published online on July 13, 2005
Carcinogenesis, doi:10.1093/carcin/bgi180

World Bank.Study: Arsenic Contamination of Groundwater in South and East Asian Countries - Towards a More Effective Operational Response.  April 2005. 

Wei, M, L Arnold, M Cano and SM Cohen. 2005.Effects of co-administration of antioxidants and arsenicals on the rat urinary bladder epithelium.
Toxicol Sci 83:237-245. 

J Zhang and R Stanforth.Langmuir.
Slow Adsorption Reaction between Arsenic Species and Goethite (alpha-FeOOH):Diffusion or Heterogeneous Surface
Reaction Control.  , March 29, 2005; 21(7): 2895-901

Zierold, KM, L Knobelock and H Anderson. 2004.
Prevalence of chronic diseases in adults exposed to arsenic-contaminated drinking water.

Am J Publ Hlth 94:1936-1937.

AI Zouboulis and IA Katsoyiannis.
Recent advances in the bioremediation of arsenic-contaminated groundwaters.   
Environ Int, February 1, 2005; 31(2): 213-9.

ABUL HASNAT MILTON,ZIAUL HASAN,S.M.SHAHIDULLAH,SINTHIA SHARMIN,M.D.JAKARIYA,MAHFUZAR RAHMAN,KEITHDEAR and WAYNE SMITHAssociation between nutritional status and arsenicosis due to chronic arsenic exposure in Bangladesh

Aguilar,J., C Dorronsoro, E Fernandez, J Fernandez, I Garcia, F Martin, and M Simon,  
Soil pollution by a pyrite mine spill in Spain:  evolution in time.,
Environ Pollut, December 1, 2004; 132(3): 395-401.Abstract

P Aguirre-Banuelos, C Escudero- Lourdes, L Carrizales, F Diaz-Barriga, and J Perez-Urizar 
Effect of acute exposure to arsenic on formalin-induced nociception andtramadol-mediated antinociception in mice. 
Proc West Pharmacol Soc, January 1, 2004; 47: 113-6.

Alkorta, I., J Hernandez-Allica, and C Garbisu.
Plants against the global epidemic of arsenic poisoning. 
Environ Int, September 1, 2004; 30(7): 949-51.

Akai,  J., Kaoru Izumi, Haruo Fukuhara, Harue Masuda, Satoshi Nakano,  Takahisa Yoshimura, Hiroaki Ohfuji, Hossain Md Anawar and Kurumi Akai.
Mineralogical and geomicrobiological investigations on groundwater arsenic enrichment in Bangladesh. 

Applied  Geochemistry, 19(2), 163-260, February 2004, 215-230.

An, Y., Z Gao, Z Wang, S Yang, J Liang, Y Feng, K Kato, M Nakano, S Okada, and K Yamanaka, 
Immunohistochemical analysis of oxidative DNA damage in arsenic-related human skin samples from arsenic-contaminated area of China.  Cancer Lett

Appleyard et al
Acidification of water ..  in Perth  
Australian Journal of Soil Research 2004  42:579-585

Case Studies in Environmental Medicine:  Arsenic Toxicity
A PDF version of the full case study

Basu, A., P. Ghosh, J. K. Das, A. Banerjee, K. Ray, and A. K. Giri. 
Micronuclei as Biomarkers of Carcinogen Exposure in Populations Exposed to Arsenic Through Drinking Water in  West Bengal, India: A Comparative Study in Three Cell Types
Cancer Epidemiol. Biomarkers Prev. 2004 13:820-827

Berg, M., H. C. Tran, T. C. Nguyen, H. V. Pham, R. Schertenleib, and W. Giger
Arsenic Contamination of Ground and Drinking Water in Vietnam: A Human Health Threat

Environ. Sci Technol. 2001,35, p. 2621-2626


Bhattacharjee, H., Carbrey, J., Rosen, B.P. and Mukhopadhyay, R.,
Drug uptake and modulation of drug sensitivity in leukemia by AQP9.
Biochem. Biophys. Res. Commun. 322, 836-841(2004)

Bhattacharya, P., A. H. Welch, K. M. Ahmed, G. Jacks and R. Naidu  (Eds.)
Arsenic in Groundwater of Sedimentary Aquifers.
Applied Geochemistry, 19(2), 163-260, February 2004.The table of contents, with links to abstracts and full text,

Blute NK, Brabander DJ, Hemond HF, Sutton SR, Newville MG, Rivers ML. 
Arsenic sequestration by ferric iron plaque on cattail roots. 
Environ Sci Technol. 2004 Nov 15;38(22):6074-7

Boffetta, P.,
Epidemiology of environmental and occupational cancer
Oncogene, August 23, 2004; 23(38): 6392-403. Abstract

M Bunderson, DM Brooks, DL Walker, ME Rosenfeld, JD Coffin, and HD Beall.
Arsenic exposure exacerbates atherosclerotic plaque formation and increases nitrotyrosine and leukotriene biosynthesis.
Toxicol Appl Pharmacol. 2004; 201: 32-39.

Bundschuh, J.,  B. Farias, R. Martin, A. Storniolo, P. Bhattacharya, J.  Cortes, G. Bonorino and R. Albouy.
Groundwater arsenic in the Chaco-Pampean Plain, Argentina: case  study from Robles county, Santiago del Estero Province
Applied  Geochemistry, 19(2), 163-260, February 2004, 231-243.


D. Canovas, R. Vooijs, H. Schat, and V. de Lorenzo.
The Role of Thiol Species in the Hypertolerance of Aspergillus sp. P37 to Arsenic.   
J. Biol.Chem.2004,279:51234-51240.

Cao X., and LQ Ma, 
Effects of compost and phosphate on plant arsenic accumulation from soils near pressure-treated wood.
Environ Pollut, December 1, 2004; 132(3): 435-42.  Abstract

Chakraborti, D., MK Sengupta, MM Rahman, S Ahamed, UK Chowdhury, MA Hossain, SC Mukherjee, S Pati, KC Saha, RN Dutta, and Q Quamruzzaman. 
Groundwater arsenic contamination and its health effects in the Ganga-Meghna-Brahmaputra plain. 
J Environ Monit, June 1, 2004; 6(6): 74N-83N.  [No abstract available]

Chen ,., S. F. Li , J.Liu , J., B. A. Diwan , C. Barrett , and M. P. Waalkes   
Chronic inorganic arsenic exposure induces hepatic global and individual gene hypomethylation: implications for arsenic hepatocarcinogenesis
Carcinogenesis 2004 25(9):1779-1786

Chen, Y-C., L. Xu, H.-J. J.Su, Y.-L. L. Guo, T. J. Smith, L. M. Ryan, M.-S. Lee, and D. C. Christiani,
Polymorphisms in GSTT1 and p53 and Urinary Transitional Cell Carcinoma in Southwestern Taiwan (Submitted)

Chen, Y., and H. Ahsan,  
Cancer Burden From Arsenic in Drinking Water in Bangladesh 
American Journal of Public Health 94(5), 741-744. May 2004

Cheng Z., Van Geen, A, Chuangyong, J., Meng, X., Siddique A., Ahmed K.M. and Ahmed K.M. 
Performance of a household-Level Arsenic removal System during 4 months Deployment in Bangladesh
Environ. Sci. Tech. 38:3442-3448 (2004)
Comment by Mukherjee et al. andresponse

Chien, C-W, et al. 2004.
Association of chromosomal alterations with arsenite-induced tumorigenicity of human HaCaT keratinocytes in nude mice.

Environ. Hlth. Perspect. 112(17)1704-1710.

Chiu HF, Ho SC, Yang CY.
Lung cancer mortality reduction after installation of tap-water supply system in an arseniasis-endemic area in Southwestern Taiwan.  
Lung Cancer. 2004 Dec;46(3):265-70.

Chowdhury AM.  
UN Millennium Project's Task Force on Child and Maternal Health.  Arsenic in Bangladesh 
Sci Am. 2004 Aug;291(2):86-91:
Comment by Amitava Mukherjee and Dipankar Chakraborti

Existing and Prospective Sorption Technologies for the Removal of Arsenic in Water.
Separation Science and Technology, 2004, vol 39, No.3, pp.603-627,

Dambies, L., R Salinaro and S. Alexandratos,
Immobilized N-Methyl-D-glucamine as an Arsenate-Selective Resin
Environ. Sci. Technol. 2004, 38, 6139-6146

Daus, B., R Wennrich, and H Weiss. 
Sorption materials for arsenic removal from water:; a comparative study.  

Water Res, July 1, 2004; 38 (12): 2948-54.

Dermatas, D., DH Moon, N Menounou, X Meng, and R Hires. 
An evaluation of arsenic release from monolithic solids using a modified semi-dynamic leaching test.  
J Hazard Mater.2004; 116: 25-38 

Drobna Z, Waters SB, Walton FS, Lecluyse EL, Thomas DJ, Styblo M. 
Interindividual variation in the metabolism of arsenic in cultured primary human hepatocytes.  
Toxicol Appl Pharmacol. 2004 Dec 1;201(2):166-77

Foust, R,D.Jr. , P. Mohapatra, A. -M. Compton-O'Brien and J. Reifel.
Groundwater arsenic in the Verde Valley in central Arizona, USA. 

Applied Geochemistry, 19(2), 163-260, February 2004, 251-255. 

Freeman, L.F.B.,  L. K. Dennis, C.  F. Lynch, P. S. Thorne, and C. L. Just. 
Toenail Arsenic Content and Cutaneous Melanoma in Iowa

American Journal of Epidemiology 2004 160(7):679- 687 alternate URL

Fujino, Y., X Guo, J Liu, L You, M Miyatake, T Yoshimura, and Japan Inner Mongolia Arsenic Pollution (JIAMP) Study Group 
Mental health burden amongst inhabitants of an arsenic-affected area in Inner Mongolia, China. 
Soc Sci Med, November 1, 2004; 59(9): 1969-73. Abstract

Gallagher,P.A.,  CA   Schwegel, A Parks, BM Gamble, L Wymer, and JT Creed.
Preservation of As(III) and As(V) in drinking water supply samples from across the United States using EDTA and acetic acid as a means of minimizing iron-arsenic coprecipitation.
Environ Sci Technol, May 15, 2004; 38(10): 2919-27.

AG Gault, J Jana, S Chakraborty, P Mukherjee, M Sarkar, B Nath, DA Polya, and D Chatterjee. 
Preservation strategies for inorganic arsenic species in high iron, low-Ehgroundwater from West Bengal, India.
Anal Bioanal Chem. 2004.


A van Geen, T Protus, Z Cheng, A Horneman, AA Seddique, MA Hoque, and KM Ahmed
Testing groundwater for arsenic in Bangladesh before installing a well.
Environ Sci Technol, December 15, 2004; 38(24): 6783-9.

A Gelman, M Trevisani, H Lu, and A van Geen.  
Direct data manipulation for local decision analysis as applied to the problem of arsenic in drinking water from tube wells in Bangladesh.
Risk Analysis, December 1, 2004; 24(6): 1597-612.


George, B., L Mathews, P Balasubramanian, RV Shaji, A Srivastava, and M Chandy
Molecular remission with arsenic trioxide in patients with newly diagnosed acute promyelocytic leukemia 
Haematologia. 89(10): 1266-7


Gourbal, B., Sonuc, N., Bhattacharjee, H., Legare, D., Sundar, S., Ouellette, M., Rosen, B.P. and Mukhopadhyay, R.,
Drug uptake and modulation of drug resistance in Leishmania by an aquaglyceroporin.
J. Biol. Chem. 279, 31010-31017(2004)

Grosz, A.E., Jeffrey N. Grossman, Robert Garrett, Peter Friske, David B. Smith, Arthur G. Darnley and Eric Vowinkel. 
A preliminary geochemical map for arsenic in surficial materials of  Canada and the United States. 

Applied Geochemistry, 19(2), 163- 260, February 2004, 257-260

Guo, H.R, N.S. Aang, H. Hu, and R.R. Monson , 
Cell Type Specificicity of Lung Cancer Associated with Arsenic Ingestion

Cancer Epidemiology, Biomarkers and Prevention 13(4),638-643 (2004) 

Hadi, A,and R Parveen. 
Arsenicosis in Bangladesh: prevalence and socio-economic correlates. 
Public Health, 2004; 118(8): 559-64.

Haugen AC, Kelley R, Collins JB, Tucker CJ, Deng C, Afshari CA, Brown JM, Ideker T, Van Houten B. 
Integrating phenotypic and expression profiles to map arsenic-response networks
 Genome Biol. 2004;5(12):R95. Epub 2004 Nov 29.

Hayakawa,T., Y Kobayashi, X Cui, and S Hirano.
A new metabolic pathway of arsenite: arsenic-glutathione complexes are substrates for human arsenic methyltransferase Cyt19.  
Arch Toxicol. 2004.

Hei T.K, and M Filipic,
Role of oxidative damage in the genotoxicity of arsenic.
Free Radic Biol Med, September 1, 2004; 37(5): 574-81. Abstract

Hemond H.F., and H.M. Solo-Gabriele,  
Children's Exposure to Arsenic from CCA-Treated Wooden Decks and Playground Structures (2004) 

Risk Analysis 24(1) 65-73

Hoeft, S.E.,  T. R. Kulp, J. F. Stolz, J.T. Hollibaugh,  and R.S. Oremland 
Dissimilatory Arsenate Reduction with Sulfide as Electron Donor:   Experiments with Mono Lake Water and Isolation of Strain MLMS-1, a Chemoautotrophic Arsenate Respirer 
Applied and Environmental Microbiology, May 2004, 70(5),  27412747


Jia, G., H Sone, N Nishimura, M Satoh, and C Tohyama.
Metallothionein (I/II) suppresses genotoxicity caused by dimethylarsinic acid.   
Int J Oncol, August 1, 2004; 25(2): 325-33.

J. Alberto Rosales-Castillo Æ Leonor C. Acosta-Saavedra Rosantina Torres Æ Jesu´ s Ochoa-Fierro Vı´ ctor H. Borja-Aburto Æ Lizbeth Lopez-Carrillo Gonzalo G. Garcia-Vargas Æ Georgina B. Gurrola Mariano E. Cebrian Æ Emma S Caldero´ n-Aranda,
Arsenic exposure and human papillomavirus response in non-melanoma skin cancer Mexican patients: a pilot study,
Published online: 3 July 2004

Jimi, S., , M. Uchiyama, A. Takaki, J. Suzumiya and S. Hara.
Mechanisms of Cell Death Induced by Cadmium and Arsenic. 

Ann. N.Y. Acad. Sci. 1011: 325-331 (2004).

Kakitani,  T., HBata, T., Kajimoto, T and Imamura Y., (2004) 
Two possible pathways for release of arsenic during pyrolysis of chromate copper arsenate (CCA) treated wood  

Journal of Hazardous Materials xxx (2004) xxx-xxx

 Karagas, M.R., TD Tosteson, JS Morris, E Demidenko, LA Mott, J Heaney, and A Schned 
Incidence of transitional cell carcinoma of the bladder and arsenic exposure in New Hampshire.
 Cancer Causes Control, June 1, 2004; 15(5): 465-72.Abstract

Kartal, S.N., and Y Imamura,
Removal of copper, chromium, and arsenic from CCA-treated wood onto chitin and chitosan.   Bioresour. Tecnol.96(3): 389-92 Feb 1 2005

Khan A., and Sracek, O., 
Arsenic enrichment in groundwater of the alluvial aquifers in  Bangladesh: an overview.
Applied Geochemistry, 19(2), 163-260, February 2004, 181-200.

Kinoshita H, Hirose Y, Tanaka T, Yamazaki Y
Oral arsenic trioxide poisoning and secondary hazard from gastric content.
Ann Emerg Med. 2004 Dec;44(6):625-7

Kumagai Y., and J Pi, 
Molecular basis for arsenic-induced alteration in nitric oxide production and oxidative stress: implication of endothelial dysfunction.  
Toxicol Appl Pharmacol, August 1, 2004; 198(3): 450-7. Abstract

Kundu,S.,  A Pal, SK Ghosh, M Mandal, and T Pal.  
Removal of arsenic from water using hardened paste of Portland cement.   
Environ Technol, March 1, 2004; 25(3): 301-9.

Shugi Kuriakose, Tony Sarvinder Singh and Kamal K. Pant.  
Adsorption of As(III) from Aqueous Solution onto Iron Oxide Impregnated Activated Alumina. 
No Journal stated

Kuroda K, Yoshida K, Yoshimura M, Endo Y, Wanibuchi H, Fukushima S, Endo G. 
Microbial metabolite of dimethylarsinic acid is highly toxic and genotoxic.
Toxicol Appl Pharmacol. 2004 Aug 1;198(3):345-53.

Kwon E, Zhang H, Wang Z, Jhangri GS, Lu X, Fok N, Gabos S, Li XF, Le XC. 
Arsenic on the hands of children after playing in playgrounds
 Environ Health Perspect. 2004 Oct;112(14):1375-80
Comment by J.C Kisel Arsenic on the hands of children and reply to comment
Environ Health Perspect. 2005 113(6):A364

Kwon E, Zhang H, Wang Z, Jhangri GS, Lu X, Fok N, Gabos S, Li XF, Le XC.  Lai, V.W., Y Sun, E Ting, WR Cullen, and KJ Reimer,
Arsenic speciation in human urine: are we all the same?, 
Toxicol Appl Pharmacol, August 1, 2004; 198(3): 297-306. Abstract

Lamm, S.H., A. Engel,, M.B. Kruse,  M. Feinleib, D.M.Byrd,  S. Lai, and  R. Wilson,
Arsenic in Drinking Water and Bladder Cancer Mortality in the United States: An Analysis  Based on 133 U.S. Counties and 30 Years of Observation
(J Occup Environ Med. 2004;46:298 306)
Comments (by Taeger, Dirk MSc; Pesch, Beate MSc, PhD) and reply to comments (J Occup Environ Med. 2004;46(10):1007-1008

Lammon CA, Hood RD. 
Effects of protein deficient diets on the developmental toxicity of inorganic arsenic in mice. 
Birth Defects Res Part B Dev Reprod Toxicol. 2004 Jun;71(3):124-34

EH Larsen, J Engman, JJ Sloth, M Hansen, and L Jorhem.
Determination of inorganic arsenic in white fish using  microwave-assisted alkaline alcoholic sample dissolution and HPLC-ICP-MS.
Anal Bioanal Chem. 2004.

SW Lee, JY Kim, JU Lee, I Ko, and KW Kim.
Removal of arsenic in tailings by soil flushing and the remediation process monitoring.  
Environ Geochem Health,2004; 26(4): 403-9

Lenoble, Veronique, Christophe Chabroullet, Raad Al Shukry, Bernard Serpaud, Veronique Deluchat, and Jean-Claude Bollinger
Dynamic arsenic removal on a MnO(2)-loaded resin. 
J Colloid Interface Sci, December 1, 2004; 280(1): 62-67.


Lewandowski, T.A., Beck, B.D., 2004.
Additional support for derivation of an acute/subchronic reference dose for arsenic

Regul Toxicol Pharmacol. 2004 Dec;40(3):370-1.

Li, Y., OP Dhankher, L Carreira, D Lee, A Chen, JI Schroeder, RS Balish and RB Meagher. 
Overexpression of Phytochelatin Synthase in Arabidopsis Leads to Enhanced Arsenic Tolerance and Cadmium Hypersensitivity
Plant and  Cell Physiology 2004 45(12):1787-1797.

Lin HT, Wang MC, Li GC. 
Complexation of arsenate with humic substance in water extract of compost. 
Chemosphere. 2004 Sep;56(11):1105-12

Liu, Z., Carbrey, J.M., Agre, P. and Rosen, B.P.
Arsenic trioxide uptake by human and rat aquaglyceroporins.
Biochem. Biophys. Res. Commun. 316, 1178-1185 (2004)

Liu, Z., Boles, E. and Rosen, B.P.
Arsenic trioxide accumulation by hexose permeases in Saccharomyces cerevisiae.
J. Biol. Chem. 279, 17312-17318 (2004)

Lokuge KM, Smith W, Caldwell B, Dear K, Milton AH. 
The effect of arsenic mitigation interventions on disease burden in Bangladesh. 
Environ Health Perspect. 2004 Aug;112(11):1172-7

Luster M.I., and PP Simeonova,
Arsenic and urinary bladder cell proliferation. 
Toxicol Appl Pharmacol, August 1, 2004; 198(3): 419-23.  Abstract

Luzi, S., M Berg, TKT Pham, HV Pham, and R Schertenleib  
Household Sand Filters for Arsenic Removal An option to mitigate arsenic from iron-rich groundwater-   T
echnical Report, Swiss Federal Institute for Environmental Science and Technology (EAWAG)

Lytle,DA.,  TJ Sorg, and C Frietch.
Accumulation of arsenic in drinking water distribution systems.   
Environ Sci Technol. 2004; 38: 5365-5372.

Maddison, D., R. C. Luque, and D. Pearce. 2004.
The Economic Cost of Arsenic Contamination of Groundwater in Bangladesh.
Water and Sanitation Program.

McArthur, J.M., D.M. Banerjee, K.A. Hudson-Edwards, R. Mishra, R. Purohit, P. Ravenscroft, A. Cronin, R.J. Howarth, A. Chatterjee, T. Talukder, D. Lowry, S. Houghton, and D.K. Chadha.
Natural organic matter in sedimentary basins and its relation to arsenic in anoxic ground water: the example of West Bengal and its worldwide implications

Applied Geochemistry, (2004). in press

Mahata, J., P. Ghosh,, J. N. Sarkar, K. Ray, A.T. Natarajan, and A. K. Giri.
 Effect of sodium arsenite on peripheral lymphocytes in vitro: individual susceptibility among a population exposed to arsenic through the drinking water.  

Mutagenesis  19(3): 223-229, May 2004

Mahlknecht, J., B. Steinich, I. Navarro de Leon (2004)
Groundwater chemistry and mass transfers in the Independence aquifer, central Mexico, by using multivariate statistics and mass-balance models
Environmental Geology, Springer Verlag Heidelberg: vol. 45:781795.

SA Mahmood and C Ball,    Defining and implementing arsenic policies in Bangladesh: possible roles for public and private sector actors.J Health Hum Serv Adm, September 1, 2004; 27(2): 158-74.

M Mahramanlioglu and K Guclu.
Equilibrium, kinetic and mass transfer studies and column operations for the removal of arsenic(III) from aqueous solutions using acid treated spent bleaching earth.
Environ Technol. 2004; 25: 1067-1076.

Mandal, B.K., Y Ogra, K Anzai, and KT Suzuki,
Speciation of arsenic in biological samples

Toxicol Appl Pharmacol, August 1, 2004; 198(3): 307-18.  Abstract

NK Mandal and R Biswas.
A study on arsenical dermatosis in rural community of West Bengal
Indian J Public Health, January 1, 2004;48(1): 30-3.

Mari F, Bertol E, Fineschi V, and Karch SB. 
Channelling the Emperor: what really killed Napoleon? 

 R Soc Med. 2004 Aug;97(8):397-9

Martinez, V., A Creus, W Venegas, A Arroyo, JP Beck, TW Gebel, J Surralles, and R Marcos
Evaluation of micronucleus induction in a Chilean population environmentally exposed to arsenic.
Mutat Res, November 14, 2004; 564(1): 65-7

Meharg,  A.A.,
Arsenic in rice - understanding a new disaster for South
-East Asia.
Trends Plant Sci, September 1, 2004; 9(9): 415-7.  Abstract

Meza, M.M.,  MJ Kopplin, JL Burgess, and AJ Gandolfi
Arsenic drinking water exposure and urinary excretion among adults in the Yaqui Valley, Sonora, Mexico.  
Environ Res, October 1, 2004; 96(2): 119-26.   Abstract

Michaud D.S., M.E. Wright, K.P. Cantor, P.R. Taylor, J. Virtamo and D. Albanes.
Arsenic Concentrations in Prediagnostic Toenails and  the Risk of Bladder Cancer in a Cohort Study of Male Smokers.
American Journal of Epidemiology  2004 160(9):853-859

Milton AH, Hasan A, Shahidullah SM, Sharmin S, Jakariya M, Rahman M, Dear K, and Smith W. (2004) 
Association between Nutritional Status and Arsenicosis due to Chronic Arsenic Exposure in Bangladesh.  
J International Environment Health Research 2004 Volume 14,  Issue 1 (in press).

Mitra, S.R., G. Mazumder, A. Basu, G. Block, R., Haque, S.Samantha,  N.Ghosh, MMH Smith, O.S.van Ehrenstein, and A.S. Smith 
Nutritional Factors and Susceptibility to Arsenic Caused Lesions in West Bengal, India.

Environmental Health PerspectivesJuly 1, 2004; 112(10): 1104-9.

 M Mkandawire, B Taubert, and EG Dudel.
Capacity of Lemna gibba L. (Duckweed) for uranium and arsenic phytoremediation
in mine tailing waters
Int J Phytoremediation, January 1, 2004; 6(4): 347-62

M. Mkandawire and E.G. Dudel. 
Accumulation of arsenic in Lemna gibba L. (duckweed) in tailing waters of two abandoned uranium mining sites in Saxony, Germany  
Sci Total Environ,2005; 336: 81-89.

Murshed,  R., R. M Douglas, , G. Ranmuthugala,  and B. Caldwell,
Clinicians' roles in management of arsenicosis in Bangladesh: interview study 
Australian National University, National Centre for Epidemiology and Population Health, Canberra, ACT 0200, Australia. BMJ  2004;328:493-494 (28 February)

Nickson, R.T., J.M. McArthur, B. Shrestha, T.O. Kyaw-Myint and D. Lowry (2004).
Arsenic, and other drinking water quality issues, Muzaffargarh, Pakistan.
Applied Geochemistry Applied Geochemistry, 20(1) :55-68.

Nico PS, Fendorf SE, Lowney YW, Holm SE, Ruby MV.  
Chemical structure of arsenic and chromium in CCA-treated wood: implications of environmental weathering. 
Environ Sci Technol. 2004 Oct 1;38(19):5253-6

O'Day, P.A., Vlassopoulos, D., Root, R., and  Rivera, N.,
The influence of sulfur and iron on dissolved arsenic concentrations in the shallow subsurface under changing redox conditions.
Proceedings of the National Academy of Sciences September 8, 2004

Oremland, R.S.,J.F.Stolz and J.T.Hollibaugh
The microbial arsenic cycle in Mono Lake,California
FEMS Microbiology Ecology 48 (2004)15 27

Pandey, P.K., S. Yadav, S. Nair and M. Pandey.
Sampling and preservation artifacts in arsenic analysis:  Implications for public health issues in developing countries. 
Current Science, 86(10), 25 May 2004, 1426-1432.

Pant, N., RC Murthy, and SP Srivastava,
Male reproductive toxicity of sodium arsenite in mice.
Hum Exp Toxicol, August 1, 2004; 23(8): 399-403,  Abstract

Patterson,R.,  L Vega, K Trouba, C Bortner, and D Germolec,
Arsenic-induced alterations in the contact hypersensitivity response in Balb/c mice.
Toxicol Appl Pharmacol, August 1, 2004; 198(3): 434-43.  Abstract

Paul BK
Arsenic contamination awareness among the rural residents in Bangladesh. 
Soc Sci Med. 2004 Oct;59(8):1741-55

Pineda-Zavaleta AP, Garcia-Vargas G, Borja-Aburto VH, Acosta-Saavedra LC, Vera Aguilar E, Gomez-Munoz A, Cebrian ME, Calderon-Aranda ES. 
Nitric oxide and superoxide anion production in monocytes from children exposed to arsenic and lead in region Lagunera, Mexico. 
Toxicol Appl Pharmacol. 2004 Aug 1;198(3):283-90.

Pizarro, I., MM Gomez, P Fodor, MA Palacios, and C Camara
Distribution and biotransformation of arsenic species in chicken cardiac and muscle tissues.
Biol Trace Elem Res, July 1, 2004; 99(1-3): 129-44.

Poddar S. 
Dietary intervention with iron and black tea infusion in reducing cytotoxicity of arsenic. 
Indian J Exp Biol. 2004 Sep;42(9):900-3

Raab A. and J. Feldmann.
Arsenic speciation in hair extracts. 
Anal Bioanal Chem, August 31, 2004; Abstract.

Rader, K.J., PM Dombrowski, KJ Farley, JD Mahony, and DM Di Toro.  
Effect of thioarsenite formation on arsenic(III) toxicity.   
Environ Toxicol Chem, July 1, 2004; 23(7): 1649-54.

Ramírez-Solís, A., Mukopadhyay, R., Rosen, B.P. and Stemmler, T.L.
Experimental and theoretical characterization of arsenite in water: Insights into the coordination environment of As-O.
Inorg Chem. 43, 2954-2959 (2004)

Rao M.V., and G Avani  
Arsenic induced free radical toxicity in brain of mice.  . 
Indian J Exp Biol, May 1, 2004; 42(5): 495-8.

Rodríguez, R., J. A. Ramos and A. Armienta.
Groundwater arsenic variations: the role of local geology and  rainfall. 
Applied Geochemistry, 19(2), 163-260, February 2004, 245- 250.

Romero, F.M., MA Armienta, and A Carrillo-Chavez,  

Arsenic sorption by carbonate-rich aquifer material, a control on arsenic mobility at Zimapán, México.  
Arch Environ Contam Toxicol, July 1, 2004; 47(1): 1-13.   Abstract

Rosales-Castillo, J.A., Leonor C. Acosta-Saavedra, Rosantina Torres, Jesus Ochoa-Fierro, Victor H. Borja-Aburto, Lizbeth Lopez-Carrillo, Gonzalo G. Garcia-Vargas, Georgina B. Gurrola, Mariano E. Cebrian, and Emma S Calderon-Aranda.
Arsenic exposure and human papillomavirus response in non-melanoma skin cancer Mexican patients: a pilot study. 
Int Arch Occup Environ Health, July 3, 2004.

Rossman, T.G., AN Uddin, and FJ Burns, 
Evidence that arsenite acts as a cocarcinogen in skin cancer. 
Toxicol Appl Pharmacol, August 1, 2004; 198(3): 394-404.  Abstract

Rossman, T.G.,  and A.N. Uddin 
Selenium prevents spontaneous and arsenite-induced Mutagenesis 
Elsevier, Inter. Congress series xx (2004) xx-xxx

Sakurai T, Ochiai M, Kojima C, Ohta T, Sakurai MH, Takada NO, Qu W, Waalkes MP, Fujiwara K. 
Role of glutathione in dimethylarsinic acid-induced apoptosis 
Toxicol Appl Pharmacol. 2004 Aug 1;198(3):354-65

Samal, A.C., G Bhar, and SC Santra.   
Biological process of arsenic removal using selected microalgae.
Indian J Exp Biol, May 1, 2004; 42  (5): 522-8.

Schoen A, Beck B, Sharma R, Dube E. 
Arsenic toxicity at low doses: epidemiological and mode of action considerations

Toxicol Appl Pharmacol. 2004 Aug 1;198(3):253-67.

Scientific American   Arsenic Crisis in Bangladesh  August 2004 p 70-75.

Sengupta M.,
Does Arsenic Consumption Influence the age at Menarche of Woman?
Indian Pediatr, 2004 41(9): 960-1

Sens, M.A., Garrett, S.H., and Somji, S 
Inorganic Cadmium- and Arsenite-Induced Malignant Transformation of Human Bladder Urothelial Cells  
Toxicological Sciences 79, 56-63 (2004).  

Shi, H.,  LG Hudson, and KJ Liu
Oxidative stress and apoptosis in metal ion-induced carcinogenesis. 
Free Radic Biol Med, September 1, 2004; 37(5): 582-93.  Abstract

Shugi, K., Singh, T S. and Pant K.K.
Equilibrium and kinetics studies on removal of arsenite by iron oxide coated activated alumina.
Ind. J. Environ. Health. 45 (1) 151-154 (2003).

Simeonova P.P.,  and MI Luster,
Arsenic and atherosclerosis.
Toxicol Appl Pharmacol, August 1, 2004; 198(3): 444-9.  Abstract
2004, Toxicology, Vol. 198, pp. 39-44],

Singh, T.S and Pant, K.K.
Adsorption of As(III) from aqueous solution onto Iron oxide coated activated alumina.

Water Quality Res. J. Canada. 39 (3)260-268 (2004)

Smith A.H. and Smith H. M
Arsenic drinking water regulations in developing countries with extensive exposure,
Toxicology, 198,. 39-44,

Spallholz, J.E., Boylan, L.M. and Rhaman, MM.
Environmental Hypothesis. Is  Poor Dietary Selenium Intake an Underlying Factor for Arsenicosis and Cancer in  Bangladesh?   
Science in the Total Environment, 323,  21-32. May (2004) Issue

Sracek, O., .P. Bhattacharya, G. Jacks, J.-P. Gustafsson and M. von Brömssen.  
Behavior of arsenic and geochemical modeling of arsenic  enrichment in aqueous environments

Applied Geochemistry, 19(2), 163-260, February 2004, 169-180.

Stephenson, J.,
Arsenic-Tainted Water,
JAMA, 2004;292:794.

Sugden, K.D., KM Rigby, and BD Martin.
Oxidative activation of the human carcinogen chromate by arsenite: A model for synergistic metal activation leading to oxidative DNA damage.
Toxicol In Vitro, December 1, 2004; 18(6): 741-8.

Sun Guifan,
Arsenic Contamination and arsenicosis in China (review)
Toxicology and Applied Pharmacology August 1, 2004; 198(3): 268-71

Sur K  and L Dunemann.  
Method for the determination of five toxicologically relevant arsenic species in human urine by liquid chromatography-hydride generation atomic absorption spectrometry. 
J Chromatogr B Analyt Technol Biomed Life Sci, August 5, 2004; 807(2): 169-76.

Suresh1, K., S. R. Prabagaran, S. Sengupta and S. Shivaji.  
Arsenic-resistant bacterium isolated  from an aquifer in West Bengal, India.  
Int J Syst Evol Microbiol   54 (2004), 1369-1375; DOI  10.1099/ijs.0.03047-0

Suzuki KT, Katagiri A, Sakuma Y, Ogra Y, Ohmichi M. 
Distributions and chemical forms of arsenic after intravenous administration of dimethylarsinic and monomethylarsonic acids to rats. 
Toxicol Appl Pharmacol. 2004 Aug 1;198(3):336-44.


Mobility of arsenic in a Bangladesh aquifer: Inferences from geochemical profiles, leaching data, and mineralogical characterization 
doi:10.1016/j.gca.2004.04.020 Geochimica et Cosmochimica Acta, Vol. 68, No. 22, pp. 4539-4557, 2004

H Takanashi, A Tanaka, T Nakajima, and A Ohki. 
Arsenic removal from groundwater by a newly developed adsorbent. 
Water Sci Technol, 2004; 50(8): 23-32.

Thomas DJ, Waters SB, Styblo M. 
Elucidating the pathway for arsenic methylation. 
Toxicol Appl Pharmacol. 2004 Aug 1;198(3):319-26

Townsend T, Tolaymat T, Solo-Gabriele H, Dubey B, Stook K, Wadanambi L. 
Leaching of CCA-treated wood: implications for waste disposal  
J Hazard Mater. 2004 Oct 18;114(1-3):75-91

Tseng, C-H.. 
The potential biological mechanisms of arsenic-induced diabetes mellitus.
Toxicol  Appl Pharmacol 1 Jun 2004 197(2): p. 67.

Tsuji, J.S., Benson, R., Schoof, R.A., Hook, G.C., 2004.
Health effect levels for assessing childhood exposure to arsenic in soil.
Reg. Toxicol. Pharmacol. 39 (2),99-110 and letter to the editor

Vela, NP and DT Keitkemper. 2004.
Total arsenic determination and speciation in infant food products by ion chromotography-inductively coupled plasma-mass spectrometry.

J.AOOC Intern., 87:244-252

Valenzuela OL, Borja-Aburto VH, Garcia-Vargas GG,Cruz-Gonzales MB, Garcia-Montalvo EA,Calderon-Aranda ES, and Del Razo LM   
Urinary Trivalent Methylated Arsenic Species in a Population Chronically Exposed to Inorganic Arsenic 
Environ Health Perspect: doi:10.1289/ehp.7519.    22 November 2004  

OL Valenzuela, VH Borja-Aburto, GG Garcia-Vargas, MB Cruz-Gonzalez, EA.  Garcia-Montalvo, ES Calderon-Aranda, and LM DelRazo.
Urinary trivalent methylated arsenic species in a population chronically exposed to inorganic arsenic.  
Environ Health Perspect, March 1, 2005; 113(3): 250-4

Vasken Aposhian H, Zakharyan RA, Avram MD, Sampayo-Reyes A, Wollenberg ML
A review of the enzymology of arsenic metabolism and a new potential role of hydrogen peroxide in the detoxication of the trivalent arsenic species. 
Toxicol Appl Pharmacol. 2004 Aug 1;198(3):327-35

Verma, R.J.,  A Vasu, and AA Saiyed,
Arsenic toxicity in mice and its possible amelioration.
J Environ Sci (China), January 1, 2004; 16(3): 447-53.Abstract

Waalkes,MP, JM Ward and BA Diwan. 2004.
Induction of tumors of the liver, lung,  ovary and adrenal in adult mice after brief maternal gestational  exposre to iinorganic arsenic. Promotional effects of postnatal phorbol ester exposure on hepatic and pulmonary, but not dermal cancers. 
Carcinogenesis 25:133-141


Waalkes MP, Liu J, Ward JM, Diwan BA. 
Animal models for arsenic carcinogenesis: inorganic arsenic is a transplacental carcinogen in mice. 
Toxicol Appl Pharmacol. 2004 Aug 1;198(3):377-84

Wanibuchi, H., EI Salim, A Kinoshita, J Shen, M Wei, K Morimura, K Yoshida, K Kuroda, G Endo, and S Fukushima,
Understanding arsenic carcinogenicity by the use of animal models.
Toxicol Appl Pharmacol, August 1, 2004; 198(3): 366-76. Abstract

Wasserman, GA, X Liu, F Parvez, H Ahsan, P Factor-Litvak, A van Green, V Slakovich, NJ Lolacono, Z Cheng, I Hussain, H Momotaj and JH Graziano. 2004.Water arsenic exposure and childrens intellectual function in Arihazar, Bangladesh.
Environ Hlth Persp 112:1329-1333 

Watanabe C, Kawata A, Sudo N, Sekiyama M, Inaoka T, Bae M, Ohtsuka R. 
Water intake in an Asian population living in arsenic-contaminated area. 
Toxicol Appl Pharmacol. 2004 Aug 1;198(3):272-82

Wu, Huile, K Manonmanii, Paul K S Lam, Shu-Huei Huang, Jian Ping Wang, and Jack C Ng
Urinary arsenic speciation and porphyrins in C57Bl/6J mice chronically exposed to low doses of sodium arsenate.
Toxicol Lett, December 1, 2004; 154(1-2): 149-157

4.  Y. Xia and J Liu. 2004.
An overview of chronic arsenism via drinkingwater in PR China.

Toxicology 198:25-29.

Yamauchi H, Aminaka Y, Yoshida K, Sun G, Pi J, Waalkes MP.
Evaluation of DNA damage in patients with arsenic poisoning: urinary 8-hydroxydeoxyguanine.  
Toxicol Appl Pharmacol. 2004 Aug 1;198(3):291-6.

Yamanaka K, Kato K, Mizoi M, An Y, Takabayashi F, Nakano M, Hoshino M, Okada S. 
The role of active arsenic species produced by metabolic reduction of dimethylarsinic acid in genotoxicity and tumorigenesis.  
Toxicol Appl Pharmacol. 2004 Aug;198(3):385-93

Yih, Ling-Huei,  Shun-Wen Hsueh, Wei-Shu Luu, Ted H Chiu, and Te-Chang Lee 
Arsenite induces prominent mitotic arrest via inhibition of G2 checkpoint activation in CGL-2 cells.
Carcinogenesis, October 7, 2004.

Yoshida, T., H Yamauchi, and G Fan Sunm
Chronic health effects in people exposed to arsenic via the drinking water: dose-response relationships in review. 
Toxicol Appl Pharmacol, August 1, 2004; 198(3): 243-52.  Abstract

Zheng, Y., M. Stute, A. van Geen, I. Gavrieli, R. Dhar, H. J. Simpson, P.  Schlosser and K. M. Ahmed.
Redox control of arsenic mobilization in Bangladesh groundwater. 
Applied Geochemistry, 19(2), 163-260, February 2004, 201-214. 

KM Zierold,KM, L Knobeloch, and H Anderson.  
Prevalence of chronic diseases in adults exposed to arsenic-contaminated drinking water.  
Am J Public Health.2004; 94:1936-1937


Abernathy, C., Thomas, J., and Calderon, R.,
Health Effects and Risk Assessment of Arsenic
J. Nutr. 133: 1536S-1538S (2003)

Ahmed MF, 2003. Arsenic Contamination: Bangladesh perspective. ISBN 984-32-0350-X. Dhaka Bangladesh: ITN Bangladesh.

Angeline S. , Margaret R. Karagas, and Joshua W. Hamilton,     
Decreased DNA repair gene expression among individuals exposed to arsenic in United States drinking water 
Int. J. Cancer 1094, 263-268 (2003)

Belluck , S L Benjamin , P Baveye , J Sampson , B Johnson
Residential Areas and Public Spaces: An Emerging Regulatory or Medical Crisis?   
International Journal of Toxicology 22(2) 109-128

Buchet, Jean-Pierre , Jean-François Heilie, Alfred Bernard,  Dominique Lison, Taiyi Jin, Xunwei Wu, Qinhu Kong and Gunnar Nordberg  
Urinary protein excretion in humans exposed to arsenic and cadmium
Int. Arch. Occup. Envir. Health (3003) 76:111-120

Caussy,  Deoraj .
Case studies of the impact of understanding bioavailability: arsenic.
 Ecotoxicology and Environmental Safety, Volume 56, Issue 1 , September 2003, Pages 164-173.

Chakraborti D,  Hussam A. and Alauddin M. (2003)  
Eds.  Special Issue On Arsenic:   Environemnt and Health Effects with Special reference to Groundwater in South Asia
Environmental Science and Health (Mercel Dekker, USA) 38(1) ( 2003 )  ( Forward )

Chakraborti, Dipenkar, Subhash C. Mukherjee, Shyamapada Pati, Mrinal K. Sengupta, Mohammad M. Rahman, Uttam K.  Chowdhury, Dilip Lodh, Chitta R. Chanda, Anil K. Chakraborti, and Gautam K. Basu.
Arsenic Groundwater Contamination in Middle Ganga Plain, Bihar, India: A Future Danger?
Environmental Health Perspectives Volume 111, Number 9, July 2003.

Yen-Ching Chen, Huey-Jen Jenny Su, Yu-Liang Leon Guo, Yu-Mei Hsueh, Thomas J. Smith, Louise M. Ryan, Meei-Shyuan Lee, and David C. Christiani,Arsenic Methylation and Bladder Cancer Risk,Cancer Causes & Control 14(4): 303-310 (2003)   download in Word format here<!--[endif]-->        Download in PDF

Yen-Ching Ch, Julia Yu-Yun Lee, and David C. Christianien, Lilian Xu, Yu-Liang Leon Guo, Huey-Jen Jenny Su, Yu-Mei Hsueh, Thomas J. Smith, Louise M. Ryan, Meei-Shyuan Lee,  Sheau-Chiou Chao, Genetic Polymorphism in p53 codon 72 and Skin Cancer in Southwestern Taiwan.Journal of Environmental Science and Health, Part A (Toxic/Hazardous Substances and Environmental Engineering)A38(1), 201-211 (2003)

Yen-Ching Chen, Yu-Liang Leon Guo, Huey-Jen Jenny Su, Yu-Mei Hsueh, Thomas J. Smith, Louise M. Ryan, Meei-Shyuan Lee, Sheau-Chiou Chao, Julia Yu-Yun Lee, and David C. Christiani,Arsenic Methylation and Skin Cancer Risk in Southwestern Taiwan, Journal of Occupational and Environmental Medicine 45(3): 241-248 (2003)        Download in PDF


Chowdhury, Jakariya M. AMR, Hossain Z, and Rahman M.
Management of chronicarsenicosis.  
 Tropical Doctor 2003 (in press).


Chowdhury Jakariya M, AMR, Hossain Z, Rahman M, Sarker Q, Khan RI, and Rahman M.    
Sustainable community-based safe water options to mitigate the Bangladesh arsenic catastrophean experience from two upzilas.
Curr Sci 2003 Jul;85(2): 141-146   local pdf file


Clarke, Tom.
Asia's arsenic crisis deepens - another Indian state succumbs to well water poisoning.
Nature Science Update, 15 February 2003


Csanaky, Iván and Zoltán Gregus.
Effect of selenite on the disposition of arsenate and arsenite in rats.

Toxicology, Volume186(1-2):33-50 , 15 April 2003

Erickson, Britt E. 
Field kits fail to provide accurate measure  of arsenic in groundwater.
Environmental Science & Technology, January 1, 2003, pp.35A-38A

Gamble, BM, PA Gallagher, JA Shoemaker, AN Parks, DM Freeman, CA Schwegel and JT Creed. 2003.
An investigation of the chemical stability of arsenosugars in basic environments using IC-ICP-MS and IC-ESI-MS/MS.

The Analyst 128:1458-1461.

Guo X, Fujino Y, Chai J, Wu K, Xia Y, Li Y, Lv J, Sun Z, Yoshimura T.
The prevalence of subjective symptoms after exposure to arsenic in drinking water in Inner Mongolia, China
Inner Mongolia Center for Endemic Disease,  Control and Research. 2003 Jul;13(4):211-5.

Hadi, Abdulhadel, Research and Evaluation Division, BRAC, Dhaka, Bangladesh.
Fighting arsenic at the grassroots: experience of BRAC's community awareness initiative in Bangladesh.
Health Policy and Planning; 18(1): 93-100, 2003.

Harder, B
Arsenic Agriculture? Irrigation may worsen Bangladesh's woes.
Science News, Nov 23, 2002 v162 i21 p325(2). Full text copyright 2002 Science Service, Inc.

Ioffredo, Christopher A.,  H. Vasken Aposhian, Mariano E. Cebrian, Hiroshi Yamauchi and Ellen K. Silbergeld.

Variability in human metabolism of arsenic.
Environmental Research  92(2):85-91, June 2003

Josephson, Julian.
The slow poisoning of Bangladesh: metals in drinking water. 
Science Selections, Environmental Health Perspectives Volume 110, Number 11, November 2002.

Kayajanian, Gary
Arsenic, cancer, and thoughtless policy.

Ecotoxicology and Environmental Safety, 55(2):139-142 , June 2003

Kumar, Sanjay. 
Millions more at risk of arsenic poisoning than previously thought. 
British Medical Journal 2003;326:466 (1 March)


Lamm, S.H.,  and  Feinleib, M.,  (2003)
Arsenic Does Not Appear to be the Risk Factor for Bladder Cancer in the Absence of both Humic Acid and High Arsenic Levels (> 350 ug/l) 
Absract for US GS conference


Mallick, Palash, Jayati Chakrabarti (Mallick) , Bibhas Guha and Anisur Rahman Khuda-Bukhsh

Ameliorating effect of microdoses of a potentized homeopathic drug, Arsenicum Album, on arsenic-induced toxicity in mice

BMC Complementary and Alternative Medicine 2003 3:7  

Milton AH, Hasan Z, Rahman A, Rahman M.

Non-cancer effects of chronic arsenicocis in Bangladesh. Preliminary results.
J Environment Science Health, Part A. 2003; A38; 301-305.

Misbahuddin Mir, Md. Kamaluddin.

Simultaneous administration of zinc and arsenic enhances arsenic accumulation in tissues.
British Medical Journal, 14 November 2002.

Ng, Jack C.; Wang, Jianping; Shraim, and Amjad
A global health problem caused by arsenic from natural sources
Chemosphere 52, (2003) 1353-1359

Pearce, D., B. Groom, C. Hepburn, and P. Koundouri. 2003. "Valuing the Future: Recentb Advances in Social Discounting." World Economics 4(2):121-141.

Pizarro, Isabel, Milagros Gómez, Maria Antonia Palacios, Carmen Cámara
Evaluation of stability of arsenic species in rice.
Analytical and Bioanalytical Chemistry, Volume 376,Number 1, May 2003, 102 - 109.

Rahman M.

The Bangladesh arsenic catastrophe-clinical manifestations.
Tropical Doctors 2003; 33:42-44.

Robson, Mark 
Methodologies for assessing exposures to metals: human host factors. 
Ecotoxicology and Environmental Safety,
Volume 56, Issue 1 , September 2003, 104-109.


Sanyal SK and Nasar SKT, (2003).

Arsenic contamination in groundwater in West Bengal (India): build-up in soil-crop system
In: Analysis and Practice in Water Resources Engineering for Disaster Mitigation, Vol. I, New Age International (P) Ltd.,  Publishers, New Delhi, pp. 216-222.

Serre, M.L., A. Kolovos, G. Christakos, and K. Modis.
An application of the holistochastic human exposure methodology to naturally occurring arsenic in Bangladesh  drinking water.
Risk Analysis, Volume 23 Issue 3 Page 515  - June 2003.

Singh, Tony Sarvinder and K. K. Pant
Equilibrium,  kinetics and thermodynamic studies for adsorption of As(III) on activated alumina
Department of Chemical Engineering, Indian Institute of Technology, Hauz Khas, New Delhi 110016, India

Smith, Meera M Hira , Timir Hore, Protap Chakraborty, DK Chakraborty, Xavier Savarimuthu, and Allan H Smith.  (2003)  
A dugwell program to provide arsenic-safe water in West Bengal,  India  preliminary results (abstract in html) (full paper in pdf).
Journal of Environmental Science & Health, Part A, Volume A38, No. 1 pp. 289-299 (2003).

J.V.S. Smitha,*, J. Jankowskia, J. Sammutb
Factors controlling the concentration and speciation of arsenic in the Stuarts Point groundwater system, northern New South Wales, Australia.
The University of New South Wales, Sydney,Australia, (2003)

Stocker, Judith, Denisa Balluch, Monika Gsell, Hauke Harms, Jessika Feliciano, Sylvia Daunert, Khurseed A. Malik,
and Jan Roelof van der Meer, (2003).
Development of a set of simple bacterial biosensors for quantitative and rapid measurements of arsenite and  arsenate in potable water.
Environmental science and technology, 37(20):4743-4750 (2003)

Sutherland, Jessica E., and Max Costa.

Epigenetics and the environment.

Annals of the New York Academy of Sciences 983:151-160 (2003)

Tsai, Song-Yen , Hung-Yi Chou, Hee-Wen The, Chao-Meei Chen and Chien-Jen Chen.

The effects of chronic arsenic exposure from drinking water on the neurobehavioral development in adolescence.
NeuroToxicology.  Volume 24, Issues 4-5 , August 2003, Pages 747-753.

Tareq, Shafi M. , S. Safiullah, H. M. Anawar, M.Majibur Rahman and T. Ishizuka.
Arsenic pollution in groundwater: a self-organizing complex geochemical process in the deltaic sedimentary environment, Bangladesh.
The Science of The Total Environment.  Volume 313, Issues 1-3 , 1 September 2003, Pages 213-226.

van Geen, Y. Zheng, R. Versteeg, M. Stute, A. Horneman, R. Dhar, M. Steckler, A. Gelman,  C. Small, H. Ahsan, J. Graziano, I. Hussein, and K. M. Ahmed
Spatial variability of arsenic in 6000 tube wells in a 25 km2 area of Bangladesh

 Water Resources Research, 35(5), 1140, doi:10.1029/2002WR001617, 2003.

van Geen, A., Y. Zheng, M. Stute, and K. M. Ahmed, 
Comment on "Arsenic mobility and groundwater extraction in Bangladesh" (II),

Science, 300, 584, 2003. (with reply by Harvey et al.  immediately following)

Warren, G.P., B. J. Alloway, N. W. Lepp, B. Singh, F. J. M.  Bochereau and C. Penny.

Field trialsto assess the uptake of arsenic by vegetables from contaminated soils and soil remediation with iron oxides.

The Science of The Total Environment 311(1-3):19-33

Yu, Winston H., Charles M. Harvey, Charles F. Harvey. 
Arsenic in groundwater in Bangladesh: A geostatistical and epidemiological framework for evaluating health effects and potential remedies
Water Resources Research, 39(6), 1146, June 2003.


AhmadJK Goldar BN Jakaiya M mand Misra S,2002. Willingness to pay for Arsenic Free Safe Drinking Water in rural Bangladesh - methodology and Results. Water Sanitation Program, South Asia.

The following publications are based on research conducted as part of the Columbia University Superfund Basic Research Program:
Health Effects and Geochemistry of Arsnic and Lead
Biomarkers. (in press, 2002) (Columbia University)

Chen Y.-C., Amarasiriwardena C.J., Hsueh Y.-M., Christiani D.C.
Stability of Arsenic Species & Insoluble Arsenic in Human Urine.

Cancer Epidemiology, Biomarkers & Prevention11(11): 1427-1433 (2002)download in Word format here   Download in pdf

Chung, J.S., Kalman, D.A., Moore, L.E., Kosnett, M.J., Arroyo, A.P.,  Beeris, M., Mazumder D.N., Hernandez, A.L., and Smith A.H., (2001)
Family Correlations of Arsenic Methylation Patterns in Children and  Parents Exposed to High concentrations of Arsenic in Drinking Water  
Env.  Health Perspect.  110(7)727-733

Van Geen, A., H. Ahsan, A. H. Horneman, R. K. Dhar, Y. Zheng, I. Hussain,  K. M. Ahmed, A. Gelman, M. Stute, H. J. Simpson, S. Wallace, C. Small, F.  Parvez, V. Slavkovich, N. J. LoIacono, M. Becker, Z. Cheng, H. Momotaj, M. Shahnewaz, A. A. Seddique, and J. H. Graziano
 Promotion of well-switching to mitigate the current arsenic crisis in Bangladesh, Bulletin of the World
Health Organization, 80, 732-737, 2002

Gordon, T., Spanier, J., Batula, J.H. and Rossman, T.G. (2002)
In vitro bio-availability of heavy metal pressure treated wood dust.
Toxicological Sciences (in press).

Charles F. Harvey , Christopher H. Swartz, A. B. M. Badruzzaman, Nicole Keon-Blute, Winston Yu, M. Ashraf Ali, Jenny Jay, Roger Beckie, Volker Niedan, Daniel Brabander, Peter M. Oates, Khandaker N. Ashfaque, Shafiqul Islam, Harold F. Hemond, and M. Feroze Ahmed (2002),
Arsenic Mobility and Groundwater Extraction in Bangladesh,  

Science; 298: 1602-1606. November 22

Herbel, MJ, J Switzer Blum, SE Hoeft, SM Cohen, LL Arnold, J Lisak, JF Stolz, and RS Oremland. (2002).
Dissimilatory arsenate reductase activity and arsenate-respiring bacteria in bovine rumen fluid, hamster feces, and the termite hindgut.
FEMS Microbiology Ecology 41: 59 - 67.

Lin N., Tang J. and Bian J. (2002)
Characteristics   of Environmental Geochemistry in the Arseniasis Area of the Inner Mongolia   of China.
  (in press)

Milton AH, and Rahman M. (2002) 
Respiratory effects and arsenic-contaminated well water in Bangladesh
International Journal Environmental   Health Research12:175-179.

Oremland, RS, SE Hoeft, N Bano, RA Hollibaugh, and J. T Hollibaugh.(2002)  
Anaerobic oxidation of arsenite in Mono Lake water and by a facultative arsenite-oxidizng chemoautotroph, strain MLHE-1.    
Applied & Environmental Microbiology 68: 4795 - 4802.

Patel, P. (2002) 
Crisis of Capacity

Harvard University senior thesis

Rahman M., Mukherjee D., Sengupta M., Chowdhury U., Lodh D., Chanda C., Roy S., MD. Selim, Quamruzzaman Q., Milton A., Shahidullah S., MD. Rahman T., Chakraborti D. (2002)
Effectiveness and Reliability of Arsenic Field  Testing Kits:  Are the Million Dollar Screening Projects Effective or  Not?

Journal of Environmental Science and Technology 2002; 36(24); 5385-5394.  DOI: 10.1021/es020591o

Rahman M. (2002)
Arsenic and Contamination of Drinking water in Bangladesh: a  public health perspective.
J. Health Pop. Nutr. 2002 Sep; 20(3):193-197

Rahman M. (2002) 

Arsenic and hypertension in Bangladesh.
BulletinWorld Health Organization 2002;80(2): 173.

Toby G. Rossman, Ahmed N. Uddin, Fredric J. Burns, and Maarten C. Bosland
Arsenite Cocarcinogenesis: An Animal Model Derived from Genetic Toxicology Studies
Environmental Health Perspectives SupplementsVolume 110, Number S5, October 2002

Van Geen, A., H. Ahsan, A. H. Horneman, R. K. Dhar, Y. Zheng, I. Hussain,  K. M. Ahmed, A. Gelman, M. Stute, H. J. Simpson, S. Wallace, C. Small, F.  Parvez, V. Slavkovich, N. J. LoIacono, M. Becker, Z. Cheng, H. Momotaj, M. Shahnewaz, A. A. Seddique, and J. H. Graziano
 Promotion of well-switching to mitigate the current arsenic crisis in Bangladesh, Bulletin of the World
Health Organization, 80, 732-737, 2002

Hui Zhang, Dongsheng MA and Xiongxi Hu

Arsenic Pollution in groundwater from Hetao Area, China

Env Geol (2002) 41: 638-643,DOI: 10.1007/s00254010044 Mitra AK et al. Arsenic-related health problems among hospital patients in SouthernBangladesh.J Health Popul Nutr 2002;20(3):198-204

To assess the health effects of arsenic poisoning and to determine the relationship among duration and severity of skin lesions, exposure dose of arsenic, and nutritional status of people, 150 patients attending the Dermatology Outpatients Department of Sher-e-Bangla Medical College Hospital, Barisal, Bangladesh, were included in this cross-sectional study. The study was conducted during January-December 2000.Records of patients were collected prospectively using a pre-tested questionnaire, which included information on demography, sources of water for drinking and cooking, duration and amount of drinking-water obtained from shallow tubewells, clinical presentations, complications, and physical and laboratory findings. Water samples from tubewells currently being used by individual patients were examined. Nine percent of the patients were unaware that arsenic- contaminated water causes diseases. Due to lack of alternative water supplies, 25%of the subjects were still drinking water from contaminated tubewells. About 18%did not complain of any clinical symptoms, except that their skin lesions were ugly-looking, and 82%had moderate or severe skin lesions. Thirty-one percent of the water samples had arsenic concentrations 10-fold higher than the permissible limit of 0.05 mg/L in Bangladesh and 50-fold higher than the WHO guideline value of 0.01 mg/L. The mean arsenic concentration in water was significantly associated with the severity of disease. Body mass index correlated inversely (r=-0.298, p=0.013) with the duration of disease after controlling for age. The findings suggest the need to enhance public awareness on negative health effects of arsenic poisoning in rural Bangladesh. From a public-health perspective, effective intervention strategies need to be developed to curb the exposure, strengthen rapid diagnostic facilities, establish effective treatment facilities in rural areas, and improve the nutritional status of people.

Rahman M. Arsenic and contamination of drinking-water in Bangladesh: A public-health perspective (Editorial). J Health Popul Nutr 2002;20(3):193-197

Geen A. van et al. Promotion of well-switching to mitigate the current arsenic crisis in Bangladesh. Bull WHO 2002;80(9): 732-737

ObjectiveTo survey tube wells and households in Araihazar upazila, Bangladesh, to set the stage for a long-term epidemiological study of the consequences of chronic arsenic exposure.

Methods Water samples and household data were collected over a period of 4 months in 2000 from 4997 contiguous tube wells serving a population of 55 000, the position of each well being determined to within + 30 m using Global Positioning System receivers. Arsenic concentrations were determined by graphite-furnace atomic-absorption spectrometry. In addition, groundwater samples collected every 2 weeks for an entire year from six tube wells were analysed for arsenic by high-resolution inductively coupled plasma-mass spectrometry.

Findings Half of the wells surveyed in Araihazar had been installed in the previous 5 years; 94% were privately owned. Only about 48% of the surveyed wells supplied water with an arsenic content below 50 mg/l, the current Bangladesh standard for drinking-water. Similar to other regions of Bangladesh and West Bengal, India, the distribution of arsenic in Araihazar is spatially highly variable (range: 5860 mg/l) and therefore difficult to predict. Because of this variability, however, close to 90% of the inhabitants live within 100 m of a safe well. Monitoring of six tube wells currently meeting the 50 mg/l standard showed no indication of a seasonal cycle in arsenic concentrations coupled to the hydrological cycle. This suggests that well-switching is a viable option in Araihazar, at least for the short term.

Conclusions Well-switching should be more systematically encouraged in Araihazar and many other parts of Bangladesh and West Bengal, India. Social barriers to well-switching need to be better understood and, if possible, overcome.

Smith AH, Lingas EO, Rahman M. Contamination of drinking-water by arsenic in Bangladesh: a public health emergency. Bull WHO 2000;78(9):1093-1103


The contamination of groundwater by arsenic in Bangladesh is the largest poisoning of a population in history, with millions of people exposed. This paper describes the history of the discovery of arsenic in drinking-water in Bangladesh and recommends intervention strategies. Tube-wells were installed to provide pure water to prevent morbidity and mortality from gastrointestinal disease. The water from the millions of tube-wells that were installed was not tested for arsenic contamination. Studies in other countries where the population has had long-term exposure to arsenic in groundwater indicate that 1 in 10 people who drink water containing 500 mg of arsenic per litre may ultimately die from cancers caused by arsenic, including lung, bladder and skin cancers. The rapid allocation of funding and prompt expansion of current interventions to address this contamination should be facilitated. The fundamental intervention is the identification and provision of arsenic-free drinking water. Arsenic is rapidly excreted in urine, and for early or mild cases, no specific treatment is required. Community education and participation are essential to ensure that interventions are successful; these should be coupled with follow-up monitoring to confirm that exposure has ended. Taken together with the discovery of arsenic in groundwater in other countries, the experience in Bangladesh shows that groundwater sources throughout the world that are used for drinking-water should be tested for arsenic.

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