Researcher Profile

My research focuses on nutrition, child health and gastrointestinal infection, particularly those that are common in children in developing countries. Identifying better or novel treatment options for diarrhea case management were major interest. The options in diarrhea case management included use of  hyposmolar ORS, antibodies, pre-and probiotic, phage therapy, and plant poly phenol.  Helicobacter pylori infection  and its role in gastric acid perturbation  and  iron deficiency anemia in children and women are other area of interests.   Recently I developed interest on gut and vaginal microbiota and  role of pre and Probiotic in mitigating l dysbiosis linked to persistent diarrhea in children and urogenital infection in women of child bearing age.

Selected publications include:

• Sarker SA,Mahalanabis D, Alam NH, Sharmin S, Khan IS, Fuchs GJ. Reduced similarity oral dehydration solution for persistent diarrhea in infants: A randomized controlled clinical trial. J Pediatrics 2001; 138:532-8.
• Sarker SA, Davidsson L^, Mahmud H, Walczyk T, Hurrell RF, Gyr N, Fuchs GJ. Helicobacter pylori infection, iron absorption, and gastric acid secretion in Bangladeshi children. Am J Clin Nutr 2004; 80:149-53.
• Davidsson L, Jamil AKM, Sarker SA, Fuchs G, Hurrel R. Human Milk as à source of ascorbic acid : no enhancing effect on its bioavailability from a complementary food consumed by Bangladeshi infants and children. Am J Clin Nutr 2004; 79:1073-7.
• Sarker SA, Sultana S, Azim T, Alam NH, Fuchs G, Brussow H, Hammarstrom L.   Lactobacillus paracasei strain ST11 has no effect on rotavirus but ameliorates the outcome of nonrotavirus diarrhoea in children from Bangladesh.Pediatrics 2005;e116:221-8.
• Sarker SA,Mahmud H, Davidsson L, Alam NH, Ahmed T, Alam N, Salam MA, Beglinger C, Gyr N, Fuchs GJ. Causal relationship of Helicobacter pylori with iron-deficiency anemia or failure of iron supplementation in children. Gastroenterology. 2008 Nov;135(5):1534-42. Epub 2008 Aug 5
• Sarker SA, S,Sattar S, Ahmed T, Beglinger C,Gyr N, Fuchs GJ. Influence of  Helicobacter pylori infection on gastric acid secretion in pre-school Bangladeshi children. Helicobacter 2012;17(5):333-9.
• Sarker SA, Sultana S, ALam NH, Bardhan PK, Winfred T, Salam MA, Hammarstrom L, Frenken K. Efficacy of a novel anti-rotavirus protein on the severity of rotavirus induced diarrhoea in male children: a randomised, double blind, placebo-controlled phase II trial. Gastroenterology. 2013 Oct;145(4):740-748.
• Sarker SA, McCallin S, Barretto C, Berger B, Piitet A, Sultana S, Krauser L, Bruttin A, Brussow H. Oral T4-Like Phage Cocktail Application To Healthy Adult Volunteers from Bangladesh "Virology 434 (2012) 222–232".
• Sarker SA, Sultana S, Pietroni M, Dover A. Safety of a Bioactive Polyphenol Dietary Supplement in Pediatric Subjects with Acute Diarrhoea.Int J Pediatr. 2015;2015:387159. doi: 10.1155/2015/387159. Epub 2015 Sep 7
• SarkerSA,SultanaS,  ReutelerG,  MoineD,  DescombesP, ChartonF,  BourdinG, McCallinS,,Ngom-BruC, ,Neville,T, AkterM, Hoq S, Qadri, F, Talukdar,K,  KassamM,  DelleyM,  Loiseau,C,  DengY, El AidyS, BergerB,  BrüssowH. Oral Phage Therapy of Acute Bacterial Diarrhea With Two Coliphage Preparations: A Randomized Trial in Children From Bangladesh.EBioMed (in press)