Researcher Profile

I am interested in research related to viral pathogens for both human and zoonotic importance. Currently I am involved in projects aiming to carry out epidemiological studies of diseases transmitted from wildlife or domestic animals to people, including highly pathogenic avian influenza A/H5N1, Nipah virus, Japanese encephalitis virus, hepatitis E virus, rotavirus. I participated in joint outbreak investigations of avian influenza in humans and poultry with other stake holders like IEDCR and FAO. I am also involved in studies aiming to understand the distribution of Norovirus in Bangladesh, genetic characterization of circulating Nipah virus, genotyping of Hepatitis C virus and viral pathogen discovery as either a PI or as co-investigator.

• Member, Graduate Biochemist Association
• Member, American Society for Microbiology
• Member, Bangladesh Society for Biochemistry and Molecular Biology
• Member, One Health, Bangladesh
• ICGEB Pre-Doctoral Fellowship 2007, International Centre for Genetic Engineering and Biotechnology

Selected publications include:

• Tyagi K, Hossain ME, Thakur V, Aggarwal P, Malhotra P, Mohmmed A, Sharma YD. Plasmodium vivax Tryptophan Rich Antigen PvTRAg36.6 Interacts with PvETRAMP and PvTRAg56.6 Interacts with PvMSP7 during Erythrocytic Stages of the Parasite. PLoS One. 2016 Mar 8;11(3):e0151065. doi: 10.1371/journal.pone.0151065. eCollection 2016. PubMed PMID: 26954579.
• Thakur V, Asad M, Jain S, Hossain ME, Gupta A, Kaur I, Rathore S, Ali S, Khan NJ, Mohmmed A. Eps15 homology domain containing protein of Plasmodium falciparum (PfEHD) associates with endocytosis and vesicular trafficking towards neutral lipid storage site. Biochim Biophys Acta. 2015 Nov;1853(11 Pt A):2856-69. doi:10.1016/j.bbamcr.2015.08.007. Epub 2015 Aug 15. PubMed PMID: 26284889.
• Kibria KM, Hossain ME, Sultana J, Sarker SA, Bardhan PK, Rahman M, Nahar S. The Prevalence of Mixed Helicobacter pylori Infections in Symptomatic and Asymptomatic Subjects in Dhaka, Bangladesh. Helicobacter. 2015 Oct;20(5):397-404. doi: 10.1111/hel.12213. Epub 2015 Mar 31. PubMed PMID: 25827337.
• Afrad MH, Matthijnssens J, Afroz SF, Rudra P, Nahar L, Rahman R, Hossain ME, Rahman SR, Azim T, Rahman M. Differences in lineage replacement dynamics of G1 and G2 rotavirus strains versus G9 strain over a period of 22 years inBangladesh. Infect Genet Evol. 2014 Dec;28:214-22. doi:10.1016/j.meegid.2014.10.002. Epub 2014 Oct 11. PubMed PMID: 25305473.
• Jain S, Rathore S, Asad M, Hossain ME, Sinha D, Datta G, Mohmmed A. The prokaryotic ClpQ protease plays a key role in growth and development of mitochondria in Plasmodium falciparum. Cell Microbiol. 2013 Oct;15(10):1660-73. doi: 10.1111/cmi.12142. Epub 2013 Apr 11. PubMed PMID: 23521916. 
• Haseen F, Chawdhury FA, Hossain ME, Huq M, Bhuiyan MU, Imam H, Rahman DM, Gazi R, Khan SI, Kelly R, Ahmed J, Rahman M. Sexually transmitted infections and sexual behaviour among youth clients of hotel-based female sex workers in Dhaka, Bangladesh. Int J STD AIDS. 2012 Aug;23(8):553-9. doi: 10.1258/ijsa.2012.011373. PubMed PMID: 22930291.
• Hossain ME, Dhawan S, Mohmmed A. The cysteine-rich regions of Plasmodium falciparum RON2 bind with host erythrocyte and AMA1 during merozoite invasion. Parasitol Res. 2012 May;110(5):1711-21. doi: 10.1007/s00436-011-2690-z. Epub 2011 Oct 27. PubMed PMID: 22033736.
• Nahar S, Kibria KM, Hossain ME, Sultana J, Sarker SA, Engstrand L, Bardhan PK, Rahman M, Endtz HP. Evidence of intra-familial transmission of Helicobacter pylori by PCR-based RAPD fingerprinting in Bangladesh. Eur J Clin Microbiol Infect Dis. 2009 Jul;28(7):767-73. doi: 10.1007/s10096-008-0699-8. Epub 2009 Feb 4. PubMed PMID: 19190943.