Research goals in enteric and respiratory infections

  • Determine the molecular mechanisms governing the environmental ecology and pathogenesis of bacterial enteric pathogens to provide leads for new preventative and therapeutic interventions
  • Study mechanisms of emergence of new pathogenic strains and their evolution
  • Elucidate the immune responses responsible for mediating immune protection against key enteric pathogens, and mechanisms to enhance protection via improved vaccines
  • Identify new vaccine antigens to provide leads for development of improved vaccines
  • Better characterise disease burden and human susceptibility for improved targeting of interventions
  • Develop and evaluate improved diagnostics to facilitate detection and treatment
  • Evaluate new vaccines for pathogens of public health importance
  • Evaluate new therapeutics to improve therapeutic outcomes
  • Develop and evaluate non-vaccine preventive interventions